This guide contains information about places where you can stop for the night when driving from Greenville, Alabama to Myrtle Beach, South Carolina. Total distance for the trip is around 562 miles with a driving time of approximately 8 hours 17 mins. Cities and towns with hotels that are on the fastest route between Greenville and Myrtle Beach are listed and shown on the map. (Driving times are approximate and will vary with traffic and weather conditions.)

99.1 miles from Greenville (1 hour 32 mins)
465 miles from Myrtle Beach (6 hours 56 mins)
Major hotel chains: Clarion Hotels, Courtyard by Marriott, Econo Lodge, Holiday Inn Express, Hampton Inn, Microtel Inns, Quality Inns, TownePlace Suites by Marriott, Hilton Garden Inn

Popular Hotels In Myrtle Beach

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Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.