This guide contains information about places where you can stop for the night when driving from Mobile, Alabama to Myrtle Beach, South Carolina. Total distance for the trip is around 685 miles with a driving time of approximately 9 hours 54 mins. Cities and towns with hotels that are on the fastest route between Mobile and Myrtle Beach are listed and shown on the map. (Driving times are approximate and will vary with traffic and weather conditions.)

126 miles from Mobile (1 hour 49 mins)
562 miles from Myrtle Beach (8 hours 17 mins)
Major hotel chains: Baymont Inn & Suites, Best Western, Comfort Inns, Days Inn, Holiday Inn Express, Hampton Inn, Quality Inns
222 miles from Mobile (3 hours 10 mins)
465 miles from Myrtle Beach (6 hours 56 mins)
Major hotel chains: Clarion Hotels, Courtyard by Marriott, Econo Lodge, Holiday Inn Express, Hampton Inn, Microtel Inns, Quality Inns, TownePlace Suites by Marriott, Hilton Garden Inn

Popular Hotels In Myrtle Beach

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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.