This guide contains information about places where you can stop for the night when driving from Yuma, Arizona to Myrtle Beach, South Carolina. Total distance for the trip is around 2331 miles with a driving time of approximately 1 day 9 hours. Cities and towns with hotels that are on the fastest route between Yuma and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

674 miles from Yuma (9 hours 19 mins)
1657 miles from Myrtle Beach (23 hours 31 mins)
Major hotel chains: Days Inn, Econo Lodge, Holiday Inn Express, Hampton Inn, Super 8, Quality Inns, Red Roof Inns
965 miles from Yuma (13 hours 15 mins)
1367 miles from Myrtle Beach (19 hours 38 mins)
Major hotel chains: Holiday Inn Express, Hampton Inn, Microtel Inns, Staybridge Suites by Holiday Inn, Marriott Hotel Brands, Wyndham Brands
1442 miles from Yuma (19 hours 53 mins)
892 miles from Myrtle Beach (12 hours 58 mins)
Major hotel chains: Courtyard by Marriott, Days Inn, Holiday Inn Express, Fairfield Inn by Marriott, Hampton Inn, Super 8, Quality Inns

Popular Hotels In Myrtle Beach

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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.