This guide contains information about places where you can stop for the night when driving from Chicago, Illinois to Myrtle Beach, South Carolina. Total distance for the trip is around 949 miles with a driving time of approximately 14 hours 16 mins. Cities and towns with hotels that are on the fastest route between Chicago and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

349 miles from Chicago (5 hours 18 mins)
606 miles from Myrtle Beach (9 hours 12 mins)
Major hotel chains: Best Western, Days Inn, Holiday Inn Express, Fairfield Inn by Marriott, Hampton Inn, Staybridge Suites by Holiday Inn, Marriott Hotel Brands, Wyndham Brands

Popular Hotels In Myrtle Beach

Book Hotels Online
or call 1-866-226-8756
Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.