This guide contains information about places where you can stop for the night when driving from Portland, Maine to Myrtle Beach, South Carolina. Total distance for the trip is around 973 miles with a driving time of approximately 15 hours 4 mins. Cities and towns with hotels that are on the fastest route between Portland and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

237 miles from Portland (3 hours 39 mins)
741 miles from Myrtle Beach (11 hours 37 mins)
Major hotel chains: Courtyard by Marriott, Days Inn, Staybridge Suites by Holiday Inn, Marriott Hotel Brands, Wyndham Brands
675 miles from Portland (10 hours 36 mins)
305 miles from Myrtle Beach (4 hours 33 mins)
Major hotel chains: Comfort Inns, Days Inn, Econo Lodge, Holiday Inn Express, Hampton Inn, Super 8, Quality Inns, Staybridge Suites by Holiday Inn, Marriott Hotel Brands, Wyndham Brands
735 miles from Portland (11 hours 30 mins)
247 miles from Myrtle Beach (3 hours 49 mins)
Major hotel chains: Baymont Inn & Suites, Best Western, Holiday Inn Express, Hampton Inn, Quality Inns, Red Roof Inns, Hilton Garden Inn

Popular Hotels In Myrtle Beach

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