This guide contains information about places where you can stop for the night when driving from Buffalo, New York to Myrtle Beach, South Carolina. Total distance for the trip is around 820 miles with a driving time of approximately 12 hours 39 mins. Cities and towns with hotels that are on the fastest route between Buffalo and Myrtle Beach are listed and shown on the map. (Driving times are approximate and will vary with traffic and weather conditions.)

627 miles from Buffalo (9 hours 33 mins)
192 miles from Myrtle Beach (3 hours 16 mins)
Major hotel chains: Courtyard by Marriott, Quality Inns, Radisson Hotels, Staybridge Suites by Holiday Inn, Marriott Hotel Brands, Wyndham Brands
707 miles from Buffalo (10 hours 40 mins)
113 miles from Myrtle Beach (2 hours 4 mins)
Major hotel chains: Days Inn, Holiday Inn Express, Fairfield Inn by Marriott, Quality Inns

Popular Hotels In Myrtle Beach

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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.