This guide contains information about places where you can stop for the night when driving from Amarillo, Texas to Myrtle Beach, South Carolina. Total distance for the trip is around 1468 miles with a driving time of approximately 21 hours 24 mins. Cities and towns with hotels that are on the fastest route between Amarillo and Myrtle Beach are listed and shown on the map. (Driving times are approximate and will vary with traffic and weather conditions.)

Popular Hotels In Myrtle Beach

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Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.