This guide contains information about places where you can stop for the night when driving from Cheyenne, Wyoming to Myrtle Beach, South Carolina. Total distance for the trip is around 1776 miles with a driving time of approximately 1 day 2 hours. Cities and towns with hotels that are on the fastest route between Cheyenne and Myrtle Beach are listed and shown on the map. (Driving times are approximate and will vary with traffic and weather conditions.)

102 miles from Cheyenne (1 hour 34 mins)
1677 miles from Myrtle Beach (1 day 1 hour)
Major hotel chains: Comfort Inns, Days Inn, Fairfield Inn by Marriott, Hampton Inn, Quality Inns
222 miles from Cheyenne (3 hours 16 mins)
1559 miles from Myrtle Beach (22 hours 56 mins)
Major hotel chains: Baymont Inn & Suites, Comfort Inns, Days Inn, Holiday Inn Express, Fairfield Inn by Marriott, Howard Johnson, Hampton Inn, Super 8, Quality Inns
885 miles from Cheyenne (12 hours 39 mins)
895 miles from Myrtle Beach (13 hours 19 mins)

Popular Hotels In Myrtle Beach

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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.