This guide contains information about places where you can stop for the night when driving from
Florence, South Carolina to Orlando, Florida.
Total distance for the trip is around 451 miles with a driving time of approximately 6 hours 22 mins.
Cities and towns with hotels that are on the fastest route between Florence and Orlando
are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)
179 miles from Florence (2 hours 35 mins)
280 miles from Orlando (4 hours 0 mins)
250 miles from Florence (3 hours 33 mins)
211 miles from Orlando (3 hours 5 mins)
310 miles from Florence (4 hours 19 mins)
141 miles from Orlando (2 hours 5 mins)
400 miles from Florence (5 hours 43 mins)
55.1 miles from Orlando (55 mins)
