This guide contains information about places where you can stop for the night when driving from Portland, Oregon to Myrtle Beach, South Carolina. Total distance for the trip is around 2938 miles with a driving time of approximately 43 hours. Cities and towns with hotels that are on the fastest route between Portland and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

1261 miles from Portland (17 hours 59 mins)
1677 miles from Myrtle Beach (1 day 1 hour)
Major hotel chains: Comfort Inns, Days Inn, Fairfield Inn by Marriott, Hampton Inn, Quality Inns
2045 miles from Portland (1 day 5 hours)
895 miles from Myrtle Beach (13 hours 19 mins)

Popular Hotels In Myrtle Beach

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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.